What changed?
A sourced timeline of research records and material development changes tracked by BACToBasics for MOTS-C. Research-publication dates and clinical-development event dates are labeled separately so they are not mistaken for the same type of update.
Tracked items
3
Research sources
2
Development entries
1
Latest recorded date
Verified 2026-09-05
Latest development activity
Verified 2026-09-05 · Preclinical / human biology evidence · No established development program
MOTS-C has substantial interest as an endogenous mitochondrial-derived peptide, but human biology measurements are not the same as a validated therapeutic development program using administered MOTS-C.
Open source ↗Latest research record by publication date
Published 2026 · Regulatory · Regulatory evidence review
FDA's review distinguishes human studies of endogenous MOTS-C from the much weaker evidence base for administering MOTS-C as a therapeutic substance.
Open source ↗Tracked timeline
Development changes are dated to the underlying milestone. Research-source entries use the study or source publication year currently stored in the Research Library; that year is not presented as the date BACToBasics added the record.
Preclinical / human biology evidence · No established development program
MOTS-C has substantial interest as an endogenous mitochondrial-derived peptide, but human biology measurements are not the same as a validated therapeutic development program using administered MOTS-C.
Regulatory · Regulatory evidence review
FDA's review distinguishes human studies of endogenous MOTS-C from the much weaker evidence base for administering MOTS-C as a therapeutic substance.
Human biology · Human biology study
This study measured endogenous MOTS-C responses in humans and supports the peptide's relevance to human biology.
Following a compound creates a clean baseline from the updates currently known. When BACToBasics later records a new research source or material development change, the My Tools update badge can surface it as new for you.
BACToBasics provides educational research organization only. A development milestone does not predict future approval, and a research record does not establish that a compound is safe, effective, approved, or appropriate for use.