Peptide Reconstitution Calculators & Guides

Tirzepatide is a dual GIP and GLP-1 receptor agonist used in FDA-approved prescription products for type 2 diabetes, chronic weight management, and certain adults with obesity and obstructive sleep apnea. This page explains how Tirzepatide works, clinical-trial evidence, comparisons with Semaglutide and Retatrutide, common safety considerations, and educational reconstitution math.

Semaglutide is a GLP-1 receptor agonist used in FDA-approved prescription products for type 2 diabetes, chronic weight management, cardiovascular risk reduction in certain adults with obesity or overweight, chronic kidney disease associated with type 2 diabetes, and certain adults with MASH and liver fibrosis. This page explains how Semaglutide works, major clinical-trial evidence, comparisons with Tirzepatide and Retatrutide, safety considerations, and educational reconstitution math.

Retatrutide is an investigational triple hormone receptor agonist being studied for obesity, type 2 diabetes, and related cardiometabolic conditions. This page explains how Retatrutide works, current clinical-trial research, commonly reported side effects, comparisons with Tirzepatide and Semaglutide, and educational reconstitution math.

AOD-9604 is an investigational 16-amino-acid peptide derived from the C-terminal region of human growth hormone and developed as a potential obesity treatment. Early animal studies reported increased fat oxidation and reduced weight gain, but the larger human obesity program did not establish meaningful weight-loss efficacy, and AOD-9604 is not FDA-approved. This page explains the evidence, safety and regulatory status, sports status, and educational reconstitution math.

Cagrilintide is an investigational long-acting amylin analog being developed for chronic weight management, both alone and in fixed combination with semaglutide. This guide separates cagrilintide-alone evidence from CagriSema data and explains current Phase 3 development, mechanism, safety context, and educational concentration math.

BPC-157 is an experimental synthetic peptide widely discussed for tendon, ligament, muscle, joint, and gastrointestinal recovery. Most published evidence remains preclinical, while human research is very limited. This page explains the current evidence, safety and regulatory status, common comparisons with TB-500, and educational BPC-157 reconstitution math.

KPV is the Lys-Pro-Val tripeptide derived from the C-terminal region of alpha-melanocyte-stimulating hormone. It is widely discussed online for inflammation and gut or skin recovery, but meaningful direct human therapeutic evidence is lacking. This guide explains the preclinical evidence, mechanism uncertainty, regulatory context, and educational concentration math.

LL-37 is the 37-amino-acid active human cathelicidin peptide derived from hCAP18. It participates in innate immunity, antimicrobial defense, inflammation, cell migration, and wound biology. Human topical wound studies exist, but LL-37 is not an FDA-approved drug, injectable safety is not established, and FDA has highlighted immunogenicity, impurity, reproductive, and potential tissue-specific protumorigenic concerns for compounded LL-37.

TB-500 is a synthetic peptide fragment derived from the actin-binding region of thymosin beta-4 and is widely discussed in injury-recovery, mobility, and performance communities. Human evidence for TB-500 itself is extremely limited, and FDA has stated that it has not identified human exposure data or clinical studies using TB-500. This page explains the difference between TB-500 and full-length thymosin beta-4, current evidence and safety limitations, anti-doping status, comparisons with BPC-157, and educational reconstitution math.

Human chorionic gonadotropin (HCG) is a glycoprotein hormone used in FDA-approved prescription products for specific fertility and hypogonadism-related indications. In males, HCG acts similarly to luteinizing hormone by stimulating testicular Leydig cells. This page explains approved medical uses, fertility and TRT-related context, safety considerations, sports status, and educational HCG reconstitution math.

CJC-1295 is an investigational growth hormone-releasing hormone (GHRH) analog studied for its ability to increase endogenous growth hormone and IGF-1 signaling. Human research is limited, and CJC-1295 is not an FDA-approved medication. This page explains the original long-acting CJC-1295 compound, the common 'with DAC' and 'no DAC' terminology, available human evidence, safety and anti-doping status, and educational reconstitution math.

Ipamorelin is an investigational growth hormone secretagogue and ghrelin-receptor agonist that has been studied for its ability to stimulate growth hormone release. Human research exists, but it is limited and does not establish the broad recovery, sleep, muscle-building, or fat-loss claims commonly discussed online. This page explains the available human evidence, safety and regulatory status, comparisons with CJC-1295, and educational reconstitution math.

Tesamorelin is a growth hormone-releasing hormone analog used in FDA-approved EGRIFTA products for the reduction of excess abdominal fat in adults with HIV-associated lipodystrophy. It stimulates endogenous growth hormone release and increases IGF-1. This page explains its approved use, clinical evidence, safety considerations, sports status, and educational reconstitution math.

IGF-1 LR3, also called Long R3 IGF-I, is a synthetic analog of insulin-like growth factor 1 designed to bind IGF-binding proteins much less strongly than native IGF-1. It is widely discussed in bodybuilding and performance communities, but human clinical evidence for the LR3 analog itself is essentially absent. This page explains what is actually known from laboratory and animal research, how LR3 differs from approved recombinant IGF-1, safety and sports considerations, and educational reconstitution math.

PEG-MGF is an experimental pegylated peptide marketed in performance and recovery communities as a longer-acting form of a synthetic mechano growth factor peptide. The terminology is easy to confuse with naturally expressed IGF-1 splice variants, and human evidence for administered PEG-MGF is essentially absent. This page separates endogenous MGF biology from synthetic MGF peptides, explains what pegylation is intended to do, reviews FDA and anti-doping status, and provides educational reconstitution math.

GHRP-2, also called pralmorelin, is a synthetic growth-hormone secretagogue that activates the ghrelin/GHS-R pathway. Human studies show acute growth-hormone release and appetite effects, but those findings do not establish bodybuilding, recovery, anti-aging, or performance benefits.

GHRP-6 is a synthetic growth-hormone secretagogue that acts through the ghrelin/GHS-R pathway. Human studies show acute growth-hormone release, but the evidence base does not establish the broad muscle, fat-loss, recovery, or anti-aging claims commonly made online.

Gonadorelin is synthetic gonadotropin-releasing hormone (GnRH), matching the native hypothalamic decapeptide that stimulates pituitary release of LH and FSH. Human gonadorelin products were historically FDA-approved for diagnostic and reproductive uses but are discontinued in the United States. Modern online gonadorelin products should not be assumed equivalent to those former approved products, and BACToBasics does not provide a fertility or testosterone protocol.

Hexarelin, also known as examorelin, is a synthetic peptidyl growth-hormone secretagogue. Human studies show potent acute GH release and effects on other pituitary-adrenal hormones, but these findings do not establish long-term performance, recovery, or anti-aging benefits.

Kisspeptin is a family of naturally occurring reproductive neuropeptides that stimulate the hypothalamic-pituitary-gonadal axis primarily by activating KISS1R and promoting endogenous GnRH signaling. Human studies show clear effects on LH and FSH release, and kisspeptin-54 has been studied as an investigational trigger for oocyte maturation in IVF. Kisspeptin products sold online are not FDA-approved therapies, and FDA has identified safety and characterization concerns for compounded kisspeptin-10.

Sermorelin is a synthetic 29-amino-acid analog of growth hormone-releasing hormone. Historical Geref products received FDA approval for pediatric growth-hormone deficiency but are now listed as discontinued products. This guide explains that regulatory history, human pharmacology, mechanism, current evidence limits, and educational concentration math.

MOTS-C is a 16-amino-acid mitochondrial-derived peptide being studied for metabolic signaling, insulin sensitivity, exercise physiology, aging biology, and related conditions. Most evidence for administered MOTS-C remains preclinical, although a Phase 2a human trial is now recruiting. This page explains the current evidence, regulatory and sports status, common claims, and educational reconstitution math.

Epitalon, also called Epithalon or Epithalone, is a synthetic tetrapeptide made from alanine, glutamic acid, aspartic acid, and glycine. It is widely discussed in longevity, telomere, circadian-rhythm, and sleep communities, but most evidence remains preclinical, cell-based, or limited human research. This page explains the current evidence, safety and regulatory status, common claims, and educational reconstitution math.

DSIP, also called delta sleep-inducing peptide or emideltide, is an experimental nine-amino-acid peptide studied mainly in small human sleep trials from the 1980s and early 1990s. The evidence for insomnia is mixed and preliminary, its proposed role as a natural human sleep factor remains unresolved, and there is no FDA-approved DSIP drug. This page explains the current evidence, FDA compounding review, safety limitations, and educational reconstitution math.

Bremelanotide, also known by the development code PT-141, is a melanocortin receptor agonist and the active ingredient in FDA-approved Vyleesi for a narrow hypoactive sexual desire disorder indication in premenopausal women. This guide separates that approved use from broader online claims and explains clinical evidence, safety context, and educational concentration math.

Elamipretide, historically known as SS-31, is a mitochondrial cardiolipin-binding peptide. FDA granted accelerated approval in 2025 to Forzinity (elamipretide) for a narrow Barth syndrome indication, which must be kept separate from broader online mitochondrial, anti-aging, exercise, or wellness claims.

Selank is a synthetic heptapeptide derived from tuftsin-related biology and is discussed for anxiety, stress, and cognition. Human studies exist, mainly from Russian clinical literature, but the evidence base is not equivalent to an FDA-approved U.S. anxiolytic therapy.

Semax is a synthetic heptapeptide derived from an ACTH fragment and is discussed for neuroprotection, cognition, and stroke recovery. Human studies exist, largely from Russian clinical literature, but the evidence base and U.S. regulatory context are very different from an FDA-approved neurological therapy.

Thymosin Alpha-1, also called thymalfasin, is a synthetic 28-amino-acid peptide investigated and used internationally as an immune-modulating therapy. It is not FDA-approved in the United States, although substantial human clinical research exists across infectious disease and immune-related settings. This guide explains the evidence, U.S. regulatory status, safety context, and educational concentration math.

Melanotan II, often shortened to MT2, is an unapproved synthetic melanocortin peptide developed to stimulate skin pigmentation. Early human research showed that it can increase tanning and can also affect sexual function, but modern tanning products sold online are unapproved and may have important safety and product-quality risks. This page explains the human evidence, regulatory status, reported adverse effects, skin and mole concerns, and educational reconstitution math.

GHK-Cu is a copper-binding tripeptide widely discussed in skin-care, wound-healing, hair, and tissue-remodeling research. The strongest human evidence is topical and remains limited, while injectable GHK-Cu has no established human safety or efficacy profile. This page explains the evidence, route-specific safety and regulatory context, common claims, and educational reconstitution math.

Melanotan I (MT-I) is the historical name for the alpha-MSH analogue now known as afamelanotide. Afamelanotide has an FDA-approved 16 mg implant product, SCENESSE, for increasing pain-free light exposure in adults with erythropoietic protoporphyria (EPP). That approval does not make online products sold as injectable or tanning 'MT1' equivalent to SCENESSE. This page separates the historical pigmentation research, approved afamelanotide use, and generic educational vial math.