What changed?

Retatrutide Research & Clinical Development Updates

A sourced timeline of research records and material development changes tracked by BACToBasics for Retatrutide. Research-publication dates and clinical-development event dates are labeled separately so they are not mistaken for the same type of update.

Tracked items

4

Research sources

2

Development entries

2

Latest recorded date

May 21, 2026

Latest development activity

TRIUMPH-1 delivered positive pivotal Phase 3 results

May 21, 2026 · Trial readout · Phase 3

Lilly reported positive topline results from TRIUMPH-1, providing the first pivotal Phase 3 obesity readout for retatrutide while the drug remained investigational.

Open source ↗

Latest research record by publication date

TRIUMPH-1 Phase 3 Results

Published 2026 · Human intervention · Industry Phase 3 report

Company-reported TRIUMPH-1 results provide late-stage human evidence for retatrutide and move the evidence base beyond early clinical development.

Open source ↗

Tracked timeline

Research and development record

Development changes are dated to the underlying milestone. Research-source entries use the study or source publication year currently stored in the Research Library; that year is not presented as the date BACToBasics added the record.

Research sourcePublished 2026

TRIUMPH-1 Phase 3 Results

Human intervention · Industry Phase 3 report

Company-reported TRIUMPH-1 results provide late-stage human evidence for retatrutide and move the evidence base beyond early clinical development.

Development changeJun 26, 2023

Phase 2 obesity trial published

Trial readout · Phase 2

The randomized Phase 2 obesity trial was published online in the New England Journal of Medicine, establishing direct mid-stage human efficacy and safety evidence for retatrutide.

Research sourcePublished 2023

Triple-Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial

Human intervention · Phase 2 randomized trial

This randomized Phase 2 trial established direct human efficacy and safety evidence for retatrutide as a triple GIP, GLP-1, and glucagon receptor agonist.

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Following a compound creates a clean baseline from the updates currently known. When BACToBasics later records a new research source or material development change, the My Tools update badge can surface it as new for you.

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BACToBasics provides educational research organization only. A development milestone does not predict future approval, and a research record does not establish that a compound is safe, effective, approved, or appropriate for use.