Development changeAug 28, 2026
FDA approved Mounjaro to reduce major cardiovascular events
Approval · Approved · United States
FDA approved Mounjaro to reduce cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke in adults with type 2 diabetes who are at high risk for these events.
Development changeDec 20, 2024
FDA approved Zepbound for obesity-associated obstructive sleep apnea
Approval · Approved · United States
FDA approved Zepbound for moderate-to-severe obstructive sleep apnea in adults with obesity, expanding tirzepatide's approved clinical context.
Research sourcePublished 2024
FDA Approves First Medication for Obstructive Sleep Apnea
Regulatory · Regulatory / approval
FDA approval expanded Zepbound's clinical context to include moderate-to-severe obstructive sleep apnea in adults with obesity.
Research sourcePublished 2022
Tirzepatide Once Weekly for the Treatment of Obesity
Human intervention · Randomized controlled trial
SURMOUNT-1 provided large randomized human evidence for tirzepatide in chronic weight management.